How Long Does a GLP-1 Vial Last?
Compounded Semaglutide Vial Shelf Life
Once opened, compounded semaglutide vials should be used within 28 days when stored in the refrigerator (36°F–46°F / 2°C–8°C). The major limiting factor over time is sterility degradation associated with piercing the stopper, independent of peptide degradation.
Compounded Tirzepatide Vial Shelf Life
Similar to semaglutide, tirzepatide vials are typically good for 28 days after opening. Beyond its recommended shelf life, medication might begin to lose potency and efficacy over time.
How to Calculate Doses Per Vial
The formula: Total vial volume (mL) × Concentration (mg/mL) = Total mg in vial. Then: Total mg ÷ Your dose (mg) = Number of doses.
Storage Tips for GLP-1 Vials
Refrigerate between 36°F and 46°F. Do not freeze, as freezing destroys the peptide's structural integrity, severely dampening its medicinal efficacy. Furthermore, keep your medication out of direct sunlight.
Frequently Asked Questions
How many doses are in a 5mg/mL semaglutide vial?
It depends on your dose and vial volume. A 2mL vial at 5mg/mL contains 10mg total.
Can I use a semaglutide vial after 28 days?
Compounded vials should be discarded 28 days after opening per standard pharmacy guidance.
Why is my vial expiring before I finish it?
This happens when your dose is low relative to the vial size.
How should I store my GLP-1 vial?
Refrigerate between 36°F and 46°F (2°C and 8°C). Do not freeze.
Disclaimer:
This tool is for educational and informational purposes only. It does not constitute medical advice. Always follow the specific storage and beyond-use date (BUD) guidance provided by your dispensing pharmacy. The 28-day rule reflects USP 797 best practices for sterile multi-dose medication.